Archive: Jun 2010

Maggots and other Medical Miracles

June 29, 2010

Leeches and maggots: Doctors’ old-fashioned little helpers Published: Tuesday, June 29, 2010, 8:00 AM     Updated: Tuesday, June 29, 2010, 9:17 AM  Evelyn Theiss, The Plain Dealer  Follow Share this story Story tools View full sizeCourtesy of Pam EggersPam Mitchell says she wouldn’t be alive today if maggots hadn’t saved her feet from amputation 10 years ago. She’s had Type I diabetes since she was a child and suffered from deep ulcers on her feet as a result. Most people’s…

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RankL OPG Pathway and Charcot Neuroarthropathy

June 25, 2010

Tuesday, June 22, 2010 Overview of the RANKL OPG Pathway Southern Arizona Limb Salvage Alliance (SALSA) www.ToeAndFlow.com Authorship: Nicholas A. Giovinco Julia Bernardini David G. Armstrong   The Receptor Activator for Nuclear Factor kappa B Ligand is believed to be an important molecule of bone metabolism. This is a natural and necessary surface-bound molecule on several types of cells, and serves to activate osteoclasts.   Overproduction of RANKL is implicated in a variety of degenerative diseases. In patients with neuropathy,…

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iPhone 4 for Wound Care?

June 25, 2010

iPhone 4 FaceTime video conferencing feature can help your doctor June 23, 2010   The highlight of the recent Steve Jobs keynote where he unveiled iPhone 4 was the video telephony feature that Apple named FaceTime. This is classic Apple, taking an existing technology – video chat, think Skype – and recasting it as a brand new invention. Predictably, many commentators scoffed that FaceTime is nothing more than marketing fluff, rather than a real innovation. But, on the other hand, if…

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Insulin Pills to be Studied

June 17, 2010

I Insulin Pills Finally in Clinical Trials After years of research and anticipation, insulin pills that could make it easier for millions of patients worldwide to manage their diabetes are moving ahead in clinical trials…. Drug manufacturers have tried for years to develop oral insulin without much success. Insulin is a peptide hormone that people with diabetes currently take by injection to bring their blood sugar to within normal levels. But doing so requires uncomfortable, inconvenient injections that can make…

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DoxyCycline as an Antii-inflamatory Agent

June 16, 2010

Video Learning – Investigation of Doxycycline as an Agent for “Wound Chemotherapy” Doxycycline is a semi-synthetic tetracycline compound. Classically, this drug is used in podiatry and wound care for its properties of antibiosis and antisepsis. There have, however, been some investigations of doxycycline and other chemically modified tetracycline species (CMTS), which demonstrate its potential as an inflammatory modulator. These qualities may prove useful within a wound environment. This is particularly so, as an inhibitor of nitric oxide (NO) production, matrix…

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Clean Teeth Prevents more than Bad Breath

June 11, 2010

Clean Teeth Prevents Heart Disease by 70% Individuals who do not brush their teeth twice a day have an increased risk of heart disease, a new study shows. Regular toothbrushing could help stave off cardiovascular disease by 70% according to a nationally-representative study…. Individuals who rarely or never brushed were 70% more likely to have a heart attack or other cardiovascular disease event (P<0.001) even after controlling for many other factors, found researchers led by Richard Watt, MSc, PhD, of University…

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